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Mizota Isao


 助教 溝田 功 
 三重大学大学院 工学研究科 分子素材工学専攻




 mail: imizota [at] chem.mie-u.ac.jp
 TEL: 059-231-9415
 FAX: 059-231-9413

Profile


【学位】   博士(工学)
【所属学会】 日本化学会 有機合成化学協会 ヨウ素学会 フルオラス科学研究会
       化学フロンティア研究会

History

2006 年3 月:学士の学位取得(三重大学)
・学位論文題目「N-アリリデンアミンへのケテンシリルアセタールとトリメチルシリルシアニドの
位置選択的1,4-1,2-二重求核付加反応に関する研究」

2008 年3 月:修士の学位取得(三重大学大学院)
・学位論文題目「N-アリリデンアミンへの1,4-1,2-二重求核付加反応とホモグルタミン酸合成への
応用に関する研究」

2008年4月〜2011年3月:三重大学大学院工学研究科・博士後期課程
・ プロリンを触媒に用いるアクロレインに対するケテンシリルアセタールとアリルボロン酸
エステルの二重求核付加反応
・ グリシン誘導体から調製したイミニウム塩に対するマンニッヒ反応
・ 金属ストロンチウムを用いるイミンおよびアルデヒドの還元的セルフカップリング反応
N-アリリデンアミンに対する1,4-1,2-二重求核付加反応
・ Asian Collaborative Forum for Women Researchers in Science and Technology, Encourage and Empower
the Next Generation ポスター賞受賞 (2008年12月)

2011 年3 月:博士(工学)の学位取得(三重大学大学院)
・ 学位論文題目「イミン類の特徴を活用する反応集積的含窒素化合物の合成」

2011 年4 月〜2012 年3 月:三重大学大学院工学研究科・学術研究員
・ 電子不足イミン類への異常付加を活用する高効率的含窒素化合物の合成
・ 公益財団法人 内藤記念科学振興財団「第28 回 内藤記念海外研究留学助成金」採択

2012 年4 月〜:三重大学大学院工学研究科・分子素材工学専攻・助教
・ 極性転換反応を活用する含窒素化合物合成の反応集積化
・ アルミ電解コンデンサの高機能化に向けた新規長鎖分岐二塩基酸の開発
・ 公益財団法人 中部電気利用基礎研究振興財団「国際交流援助」採択
・ 8th International Conference on Novel Materials and their Synthesis (NMS-VIII)にてIUPAC Poster Prize受賞(2012年10月)
・ 第93春季年会(2013) 優秀講演賞受賞 (立命館大、滋賀、2013)
・ 2013年度 有機合成化学協会 東海支部奨励賞受賞
・ 研究成果展開事業 研究成果最適展開支援プログラム A-STEP 「平成25年度 第1回 FSステージ」採択
・ 公益財団法人 服部報公会「平成25年度 工学研究奨励援助金」採択
・ 公益財団法人 豊田理化学研究所「平成26年度 豊田理研スカラー」採択
・ 公益財団法人 岡三加藤文化振興財団「平成27年度 研究助成」採択
・公益財団法人 住友財団「2015年度基礎科学研究助成」採択

Publications

33) "Tandem N,N-Dialkylation Reaction of N-Trimethylsilyl α-Iminoesters Utilizing an Umpolung Reaction and
Characteristics of the Silyl Substituent: Efficient Synthesis of Pyrrolidine, Piperidine, and Iminodiacetate"
Isao Mizota, Yurie Tadano, Yusuke Nakamura, Tomoki Haramiishi, Miyuki Hotta, Makoto Shimizu,
Org. Lett
. 2019, 21, in press.

32) "Efficient One-pot Syntheses of 3-Amino-2-pyrones and 3-Amino-5,6-dihydro-2-pyridones from
β,γ-Unsaturated α-Iminoesters: Application to the Synthesis of A Tricyclic Pyranoindole"
Kenta Nakahama, Misato Suzuki, Mami Ozako, Isao Mizota, Makoto Shimizu, Asian J. Org. Chem. 2018,
7, 910-913.

31) "Umpolung Reaction of α-Imino Thioesters and the Subsequent C-C Bond Formation with the Unexpected
Alkylthio Rearrangement"
Isao Mizota, Chihiro Ueda, Yun Tesong, Yusuke Tsujimoto, Makoto Shimizu, Org. Lett. 2018, 20, 2291-2296.

30) "Synthesis of 1,2-Diamino Acid Derivatives Utilizing Diastereoselective Tandem N-Alkylation/Homo- and
Cross-addition Reaction of α-Aldimino Thioesters"
Isao Mizota, Yuji Nakajima, Asako Higashino, and Makoto Shimizu, Arab. J. Sci. Eng. 2017, 42, 4249-4261.

29) "Development of Novel Reaction Utilizing Iodination Ability of TiI4"
Iwao Hachiya, Isao Mizota, Makoto Shimizu, J. Synth. Org. Chem. Jpn. 2017, 75, 1226-1237.

28) "Synthesis of δ-Lactone and Amino Acid Frameworks Utilizing the Umpoled Reactivity of β,γ-Alkenyl
α-Iminoester"
Mami Kawanishi, Isao Mizota, Kana Aratake, Hirotaka Tanaka, Kenta Nakahama, Makoto Shimizu, Bull. Chem.
Soc. Jpn
2017, 90, 395-403.

27) "SYNTHESIS OF MULTI-SUBSTITUTED 1,4-BENZOXAZINE USING AN UMPOLUNG REACTION
WITH 2-OXO-1,4-BENZOXAZINE-3-CARBOXYLATES"
Takanori Tanaka, Isao Mizota, Makoto Shimizu, Heterocycles 2017, 95, 830-843.

26) "Titanium tetraiodide-mediated diastereoselective iodo-aldol and Mannich reactions of γ-alkoxy-α,β-alkynyl
ketone derivatives"
Kai Yashiro, Shingo Ito, Shota Kayaki, Keito Sakata, Isao Mizota, Iwao Hachiya, Makoto Shimizu,
Tetrahedron
2016, 72, 6875-6885.

25) "Exploration into a New Dicarboxylic Acid Derived from Ricinoleic Acid for the Aluminum Electrolytic
Capacitors of High Performance"
Isao Mizota, Satoshi Umeshima, Sei Matsunaga, Rinpei Isomura, Kenta Nakahama, Makoto Shimizu, Yorozu
Yokomori, Tokihiro Umemura, Noburo Kuroki, Junichi Kiyosawa, Hiroyuki Tanaka, Bull. Chem. Soc.Jpn. 2016,
89, 1368-1374.

24) "FORMAL TOTAL SYNTHESIS OF ARTOCARPIN"
Isao Mizota, Kana Taniguchi, Makoto Shimizu, Heterocycles 2016, 93, 310-322.

23) "Umpolung Reactions of α-Imino Esters: Useful Methods for the Preparation of α-Amino Acid Frameworks"
Isao Mizota, Makoto Shimizu, Chem. Rec. 2016, 16, 688-702.

22) "Highly efficient sequential N,N,C-trialkylation of α-N-acyloxyimino esters"
Isao Mizota, tsuya Maeda, Makoto Shimizu, Tetrahedron 2015, 71, 5793-5799.

21) "N-Alkylation of α-Iminophosphonates and Application to Horner-Wadsworth-Emmons Reaction"
Makoto Shimizu, Masasato Tateishi, and Isao Mizota, Chem. Lett. 2014, 43, 1752-1754.

20) "Integrated reactions based on the sequential addition to α-imino esters"
Kaichiro Koyama, Isao Mizota, and Makoto Shimizu, Pure Appl. Chem. 2014, 86, 755-764.

19) "Tandem N-Alkylation/Vinylogous Aldol Reaction of β,γ-Alkenyl α-Iminoester"
Hirotaka Tanaka, Isao Mizota and Makoto Shimizu, Org. Lett. 2014, 16, 2276-2279.

18) "TWO-STEP SYNTHESIS OF 3,4-ETHYLENEDIOYTHIOPHENE (EDOT) FROM 2,3-BUTANEDIONE ”
Iwao Hachiya, Toshihiro Yamamoto, Tatsuhiko Inagaki, Tomohiro Matsumoto, Atsushi Takahashi, Isao Mizota
and Makoto Shimizu, Heterocycles 2014, 88, 607-612.

17) "Regioselective Tandem N-Alkylation/C-Acylation of β,γ-Alkynyl α-Imino Esters"
Isao Mizota, Yuri Matsuda, Satoshi Kamimura, Hirotaka Tanaka, and Makoto Shimizu, Org. Lett. 2013, 15,
4206-4209.

16) “Tandem N-Alkylation-Addition Reaction of α-Aldimino Ester and Application to a New Flow System”
Takanori Sano, Isao Mizota and Makoto Shimizu, Chem. Lett. 2013, 42, 995-997.

15) “Highly Diastereoselective Tandem N-Alkylation-Mannich Reaction of α-Imino Esters”
Makoto Shimizu, Daiji Kurita, and Isao Mizota, Asian J. Org. Chem. 2013, 2, 208-211.

14) “Synthesis of Indolin-3-ones and Tetrahydro-4-quinolones from α-Imino Esters”
Makoto Shimizu, Yuki Takao, Haruna Katsurayama, and Isao Mizota, Asian J. Org. Chem. 2013, 2, 130-134.

13) “Integrated reactions using addition to conjugated imines and iminium salts”
Takafumi Nishi, Isao Mizota, and Makoto Shimizu, Pure Appl. Chem. 2012, 84, 2609-2617.

12) “SYNTHESIS OF NITROGEN-CONTAINING HETEROCYCLES USING CONJUGATE ADDITION
REACTIONS OF NUCLEOPHILES TO α,β-UNSATURATED IMINES”
Iwao Hachiya, Isao Mizota, and Makoto Shimizu, Heterocycles 2012, 993-1016.

11) “Synthesis of γ,δ-unsaturated quaternary α-alkylamino acids using umpolung reaction and Claisen
rearrangement”
Isao Mizota, Katsuki Tanaka, Makoto Shimizu, Tetrahedron Lett. 2012, 53, 1847-1850.

10) “Transformation of the Organic Molecules with Titanium Iodide”
Makoto Shimizu, Takafumi Nishi, Isao Mizota and Iwao Hachiya, Bulltein of the Tokai Chemical Industry
Society
, 2012, 272, 4-9.

9) “Reductive aminopropylation of ketene silyl (thio)acetals leading to the synthesis of δ-amino esters”
Isao Mizota, Shun Agatani, Iwao Hachiya, Makoto Shimizu, Tetrahedron Lett. 2011, 52, 5388-5391.

8) “Double Nucleophilic Addition to Acrolein with Ketene Silyl Acetals and Allylborolanes Catalyzed by Proline”
Makoto Shimizu, Mami Kawanishi, Akinori Itoh, Isao Mizota, and Iwao Hachiya, Chem. Lett. 2011, 40,
862-863.

7) “Efficient Mannich Reaction Using Iminium Salts Generated from Glycine Derivatives”
Makoto Shimizu, Toshiki Kusunoki, Mari Yoshida, Koichi Kondo, and Isao Mizota, Chem. Lett. 2011, 40,
351-353.

6) Selected by the Editorial Board of Synfacts (Synfacts 2010, 11, 1292.) "Use of N-Allylidene-1,1-
diphenylethanamine as Acrolein Synthon in the Double Nucleophilic Addition Reaction of Ketene Silyl
(Thio)acetals and Allylborolanes "
Makoto Shimizu, Mami Kawanishi, Isao Mizota, and Iwao Hachiya, Org. Lett. 2010, 12, 3571-3573.

5) “Use of N-Allylidene-1,1-diphenylethanamine as a Latent Acrolein Synthon in the Double Nucleophilic
Addition Reaction of Ketene Silyl (Thio)acetals and Allylborolanes”
Makoto Shimizu, Mami Kawanishi, Isao Mizota, and Iwao Hachiya, Org. Lett. 2010, 12, 3571-3573.

4) “Reductive Self-coupling Reaction of Imines and Aldehydes Induced by Strontium Metal“
Norikazu Miyoshi, Tadashi Kohno, Makoto Wada, Sei Matsunaga, Isao Mizota, and Makoto Shimizu,
Chem. Lett. 2009, 38, 984-985.

3) “N-Allylideneamines Derived from Acrolein: Synthesis and Use as Acceptors of Two Nucleophiles”
Isao Mizota, Yuri Matsuda, Iwao Hachiya, and Makoto Shimizu, Eur. J. Org. Chem. 2009, 4073-4084.

2) “Conjagated imines and iminium salts as versatile acceptors of nucleophiles“
Makoto Shimizu, Iwao Hachiya and Isao Mizota, Chem. Commun. 2009, 874-889.

1) “Synthesis of N-Allylideneamines and Their Use for the Double Nucleophilic Addition of Ketene Silyl
(Thio)acetals and Trimethylsilyl Cyanide”
Isao Mizota, Yuri Matsuda, Iwao Hachiya, and Makoto Shimizu, Org. Lett. 2008, 10, 3977-3980.
     

Symposium

188) (3PA-029)"Diastereoselective Synthesis of α-Amino Amide Using Umpolung Reaction of N-Sulfinyl-α-
Imino Amide"
The 99th Annual Meeting of The Chemical Society of Japan, March 16-19, 2019, Konan University, Hyogo,
Japan Miyuki Hotta, 〇Hiroya Nakazato,Isao Mizota, Makoto Shimizu, and Iwao Hachiya

187) (3PA-021)"Umpolung Reaction of N-Silyl-α-Imino Ester"
The 99th Annual Meeting of The Chemical Society of Japan, March 16-19, 2019, Konan University, Hyogo,
Japan Isao Mizota,〇Kai Ogata, and Iwao Hachiya

186) (3PA-014)"Synthesis of γ-Lactams Using Umpolung Amination/Cyclization Reactions of 4,5-Dihydro-
1H-pyrazole-3-carboxylate Derivatives"
The 99th Annual Meeting of The Chemical Society of Japan, March 16-19, 2019, Konan University, Hyogo,
Japan Mayuko Mori, 〇Kazuho Okada,Isao Mizota, and Iwao Hachiya

185) (3PA-013)"Claisen Rearrangement Utilizing Umpolung Reaction of α-Imino Allyl Esters and Its Application"
The 99th Annual Meeting of The Chemical Society of Japan, March 16-19, 2019, Konan University, Hyogo,
Japan Takashi Aoki, 〇Sakiho Sumikura,Isao Mizota, Makoto Shimizu and Iwao Hachiya

184) (3PA-011)"The Umpolung Reaction of Iminomalonate"
The 99th Annual Meeting of The Chemical Society of Japan, March 16-19, 2019, Konan University, Hyogo,
Japan Tomoki Haramiishi, 〇Yuuki Yasumura,Isao Mizota, Makoto Shimizu, and Iwao Hachiya

183) (2F1-10)"A Novel Synthesis of 3-Aminofurans from α-Amino Dienyl Ester Derivatives"
The 99th Annual Meeting of The Chemical Society of Japan, March 16-19, 2019, Konan University, Hyogo,
Japan 〇Shobu Yamasaki, Isao Mizota, Makoto Shimizu, and Iwao Hachiya

182) (2F1-09)"Synthesis of Tetramic Acid Derivatives via Umpolung Reaction of γ-Hydrazono β-Keto Ester"
The 99th Annual Meeting of The Chemical Society of Japan, March 16-19, 2019, Konan University, Hyogo,
Japan 〇Miki Maeda, Isao Mizota, Makoto Shimizu, and Iwao Hachiya

181) (2F1-08)"Synthesis of Oxindoles Using Umpolung Amination/Cyclization Reactions of 1H-Indazole-3-
carboxylates"
The 99th Annual Meeting of The Chemical Society of Japan, March 16-19, 2019, Konan University, Hyogo,
Japan 〇Mayuko Mori, Isao Mizota, Makoto Shimizu, and Iwao Hachiya

180) (1F4-46)"Sequential N,N,C-Trialkylation of α-Oxime Ester Using a Flow System"
The 99th Annual Meeting of The Chemical Society of Japan, March 16-19, 2019, Konan University, Hyogo,
Japan 〇Kazuki Ota, Isao Mizota, Makoto Shimizu, and Iwao Hachiya

179) (1E6-09)"Integrated Synthesis of Nitrogen Containing Compounds Utilizing Umpolung Reaction of
β,γ-Alkenyl α-Iminoesters"
The 99th Annual Meeting of The Chemical Society of Japan, March 16-19, 2019, Konan University, Hyogo,
Japan 〇Isao Mizota, Makoto Shimizu, and Iwao Hachiya

178) (1E6-08)"The Umpolung Reaction of α-Iminocarbonyl Compounds Having a Thiazoline Skeleton"
The 99th Annual Meeting of The Chemical Society of Japan, March 16-19, 2019, Konan University, Hyogo,
Japan 〇Ryou Fusayama,Isao Mizota, Makoto Shimizu, and Iwao Hachiya

177) (1E6-07)"The Umpolung Reaction of α-Iminoamide Having a Thiazoline Skeleton"
The 99th Annual Meeting of The Chemical Society of Japan, March 16-19, 2019, Konan University, Hyogo,
Japan 〇Misato Suzuki,Isao Mizota, Makoto Shimizu, and Iwao Hachiya

176) (1PA44) "Total Synthesis of the Bioactive Compound Utilizing Umpolung Reaction of α-Hydrazonoester"
49th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 3-4, 2018,
Nagoya University, Aichi, Japan 〇Shunsuke Mizutani, Isao Mizota, Makoto Shimizu and Iwao Hachiya

175) (1PA21)"Synthesis of 3-Aminofurans from α-Aino Dienylester Derivatives"
49th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 3-4, 2018,
Nagoya University, Aichi, Japan 〇Shobu Yamasaki, Isao Mizota, Makoto Shimizu and Iwao Hachiya

174) (1PA15)"Umpolung Reaction of 1H-Indazole-3-carboxylate Derivatives"
49th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 3-4, 2018,
Nagoya University, Aichi, Japan 〇Mayuko Mori, Isao Mizota, Makoto Shimizu and Iwao Hachiya

173) (FP-13) "The novel synthesis of 3-aminofurans from α-amino dienyl ester derivatives"
The 8th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2018), September 26-27,
2018, Mie University, Mie 〇Shobu Yamasaki, Isao Mizota, Makoto Shimizu and Iwao Hachiya

172) (FP-12) "Umpolung reaction of 1H-indazole-3-carboxylates"
The 8th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2018), September 26-27,
2018, Mie University, Mie 〇Mayuko Mori, Isao Mizota, Makoto Shimizu and Iwao Hachiya

171) (FP-11) "Total synthesis of bioactive compound utilizing umpolung reaction of α-hydrazonoester"
The 8th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2018), September 26-27,
2018, Mie University, Mie 〇Shunsuke Mizutani, Isao Mizota, Makoto Shimizu and Iwao Hachiya

170) (FP-9) "Umpolung reaction of α-hydrazono ester using Grignard reagent"
The 8th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2018), September 26-27,
2018, Mie University, Mie 〇Toshiki Nagato, Isao Mizota, Makoto Shimizu and Iwao Hachiya

169) (FP-8) "Asymmetric Claisen rearrangement utilizing umpolung reaction of α-imino allyl esters"
The 8th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2018), September 26-27,
2018, Mie University, Mie 〇Takashi Aoiki, Isao Mizota, Makoto Shimizu and Iwao Hachiya

168) (FO-2) "O-Alkylation reaction of α-keto amides for synthesis of α-alkoxy amides"
The 8th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2018), September 26-27,
2018, Mie University, Mie 〇Miyuki Hotta, Isao Mizota, Makoto Shimizu and Iwao Hachiya

167) (FO-1) "Umpolung Reaction of N-silyl-α-Imino Ester"
The 8th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2018), September 26-27,
2018, Mie University, Mie 〇Tomoki Haramiishi, Isao Mizota, Makoto Shimizu and Iwao Hachiya

166) "Synthesis of nitrogen-containing compounds utilizing umpolung reaction"
The 7th Chemical Frontier Workshop, September 1-2, Hokkaido University, Hokkaido, Japan, 〇Isao Mizota

165) (P-46) “Development of the Tandem Reaction Utilizing N-Alkylation of β,γ-Alkenyl α-Imino ester”
113th Symposium on Organic Synthesis, Japan, June 6-7, 2018, Nagoya University, Aichi, Japan ○Mami
Ozako, Kenta Nakahama, Isao Mizota, Iwao Hachiya, and Makoto Shimizu

164) (3H5-58)"Umpolung Reaction of α-Hydrazonoester: Synthesis of α-Aminoamide and Total Synthesis of
Bioactive Compound"
The 98th Annual Meeting of The Chemical Society of Japan, March 20-23, 2018, Nihon University, Chiba,
Japan 〇Syunsuke Mizutani, Isao Mizota, and Makoto Shimizu

163) (3H5-10)"Asymmetric Claisen Rearrangement Utilizing Umpolung Reaction of α-Imino Allyl Esters"
The 98th Annual Meeting of The Chemical Society of Japan, March 20-23, 2018, Nihon University, Chiba,
Japan Isao Mizota, 〇Takashi Aoki, and Makoto Shimizu

162) (3H5-08)"Synthesis of 3-Amino-2-pyrone by Tandem N-Alkylation/vinylogous Aldol Reaction of
β,γ-Alkenyl α-Iminoester"
The 98th Annual Meeting of The Chemical Society of Japan, March 20-23, 2018, Nihon University, Chiba,
Japan 〇Kenta Nakahama, Isao Mizota, and Makoto Shimizu

161) (2PC-137)"Umpolung of α-Acyloxyimino Ester Using a Flow System"
The 98th Annual Meeting of The Chemical Society of Japan, March 20-23, 2018, Nihon University, Chiba,
Japan Shinya Fukumoto, 〇Kazuki Ota, Isao Mizota, Iwao Hachiya and Makoto Shimizu

160) (2PC-051)"Umpolung Reaction of N-Silyl α-Imino Amide"
The 98th Annual Meeting of The Chemical Society of Japan, March 20-23, 2018, Nihon University, Chiba,
Japan Tomoki Haramiishi, 〇Daiki Yamamoto, Isao Mizota, and Makoto Shimizu

159) (2PC-050)"Umpolung Reaction of β,γ-unsaturated-α-hydrazonoester"
The 98th Annual Meeting of The Chemical Society of Japan, March 20-23, 2018, Nihon University, Chiba,
Japan 〇Toshiki Nagato, Isao Mizota, and Makoto Shimizu

158) (2PC-042)"N-Alkylation / Coupling Reaction of β,γ-Unsaturated α-Iminoester"
The 98th Annual Meeting of The Chemical Society of Japan, March 20-23, 2018, Nihon University, Chiba,
Japan Isao Mizota, 〇Ryo Fusayama, Mami Kawanishi, and Makoto Shimizu

157)(2PC-041)"Umplung Reaction of γ-Hydrazono β-Keto Ester"
The 98th Annual Meeting of The Chemical Society of Japan, March 20-23, 2018, Nihon University, Chiba,
Japan Yusuke Nakamura, 〇Miki Maeda, Isao Mizota, and Makoto Shimizu

156) (2PC-017)"Synthesis of δ-Lactam by Tandem N-Alkylation/vinylogous Mannich Reaction of
β,γ-Alkenyl α-Iminoester"
The 98th Annual Meeting of The Chemical Society of Japan, March 20-23, 2018, Nihon University, Chiba,
Japan Kenta Nakahama, 〇Misato Suzuki, Mami Kawanishi, Isao Mizota, and Makoto Shimizu

155) (2PC-016)"Synthesis of Oxindoles Using Umpolung Amination/Cyclization Reactions of
1H-Indazole-3-carboxylates"
The 98th Annual Meeting of The Chemical Society of Japan, March 20-23, 2018, Nihon University, Chiba,
Japan 〇Mayuko Mori, Isao Mizota, and Makoto Shimizu

154) (2PC-014)"The Umpolung Reaction of Iminoketone Having a Thiazoline Skeleton"
The 98th Annual Meeting of The Chemical Society of Japan, March 20-23, 2018, Nihon University, Chiba,
Japan Isao Mizota, 〇Wakana Suzuki, and Makoto Shimizu

153) (2H5-12)"Umpolung Reaction of α-Imino Thioesters and the Subsequent C-C Bond Formation with the
Unexpected Alkylthio Rearrangement"
The 98th Annual Meeting of The Chemical Society of Japan, March 20-23, 2018, Nihon University, Chiba,
Japan 〇Isao Mizota and Makoto Shimizu

152) (2H6-05)"Umpolung of α-Sulfoxyimino Ester Using a Flow System"
The 98th Annual Meeting of The Chemical Society of Japan, March 20-23, 2018, Nihon University, Chiba,
Japan 〇Shinya Fukumoto, Isao Mizota, Iwao Hachiya, and Makoto Shimizu

151) (2H5-02)"Diastereoselective Synthesis of α-Amino Amide Using the Umpolung Reaction of α-Hydrazono
Ester"
The 98th Annual Meeting of The Chemical Society of Japan, March 20-23, 2018, Nihon University, Chiba,
Japan 〇Yusuke Nakamura, Isao Mizota, and Makoto Shimizu

150) (P-10)"Umpolung Reaction of α-Imino Ester Using a Flow System"
The 11th International Symposium on Integrated Synthesis (ISONIS-11)
The 3rd International Synmposium on Middle Molecular Strategy (ISMMS-3), November 15-17, 2017, Hyogo,
Japan 〇Shinya Fukumoto, Isao Mizota, Iwao Hachiya, and Makoto Shimizu

149) (2PB26)"Synthesis of 3-Amino-2-Pyrone by Tandem N-Alkylation/Vinylogous Aldol Reaction of
β,γ-Alkenyl-α-Iminoester"
48th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 11-12, 2017,
Gifu University, Gifu, Japan 〇Kenta Nakahama, Isao Mizota and Makoto Shimizu

148) (1PA24)"Umpolung reaction of N-Silyl-α-Imino Ester Using Several Nucleophiles"
48th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 11-12, 2017,
Gifu University, Gifu, Japan 〇Yusuke Nakamura, Isao Mizota and Makoto Shimizu

147) (FP-14) "Umpolung Reaction of α-Imino Ester Using a Flow System"
The 7th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2017), September 27-28,
2017, Mie University, Mie 〇Shinya Fukumoto, Isao Mizota, Iwao Hachiya and Makoto Shimizu

146) (FP-13) "Synthesis of 3-Amino-2-Pyrone by Tandem N-Alkylation/Vinylogous Aldol Reaction of
β,γ-Alkenyl-α-Iminoester"
The 7th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2017), September 27-28,
2017, Mie University, Mie 〇Kenta Nakahama, Isao Mizota and Makoto Shimizu

145) (FO-2) "Umpolung reaction of N-Silyl-α-Imino Ester Using Several Nucleophiles"
The 7th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2017), September 27-28,
2017, Mie University, Mie 〇Yusuke Nakamura, Isao Mizota and Makoto Shimizu

144) (8) "Umpolung Reaction of α-Iminoester and Its Applicaton to Flow System Group"
Grant-in-Aid for Scientific Research on Innovative Areas, Middle molecular strategy: Creation of higher
bio-functional molecules by integrated synthesis, The forth symposium for young people, August 18-19, 2017,
Sendai, Japan 〇Isao Mizota

143) (2PB-041) "Tandem Reaction and Its Applicaton Utilizing Umpolung Reaction of the α-Imino Thioester
Having an N-m-Methoxyphenyl Group"
The 97th Annual Meeting of The Chemical Society of Japan, March 16-19, 2017, Keio University, Kanagawa,
Japan Yusuke Yanagi, 〇Shobu Yamasaki, Isao Mizota and Makoto Shimizu

142) (2PB-030) "Diastereoselective Tandem N-Alkylation/ Cross-Coupling Reaction of α-Aldimino Thioesters"
The 97th Annual Meeting of The Chemical Society of Japan, March 16-19, 2017, Keio University, Kanagawa,
Japan Asako Higashino, 〇Toshiki Nagato, Isao Mizota and Makoto Shimizu

141) (2PB-025) "N,N,C-Trialkylation Using Umpolung Reaction of α-Imino Thioester With Organometallic
Reagents"
The 97th Annual Meeting of The Chemical Society of Japan, March 16-19, 2017, Keio University, Kanagawa,
Japan Yusuke Tsujimoto, 〇Tsubasa Yamaguchi, Isao Mizota and Makoto Shimizu

140) (2PB-024) "Umpolung Reaction of N-Silyl-α-imino Ester Followed by Intramolecular Cyclization"
The 97th Annual Meeting of The Chemical Society of Japan, March 16-19, 2017, Keio University, Kanagawa,
Japan Yurie Tadano, 〇Tomoki Haramiishi, Isao Mizota and Makoto Shimizu

139) (2PB-022) "Umpolung Reaction of N-Sulfinyl-α-imino Amide"
The 97th Annual Meeting of The Chemical Society of Japan, March 16-19, 2017, Keio University, Kanagawa,
Japan Shota Uchimizu, 〇Miyuki Hotta, Isao Mizota and Makoto Shimizu

138) (2PB-020) "Umpolung Reaction of α-Hydrazonoester: Synthesis of α-Aminoamide and It's Application"
The 97th Annual Meeting of The Chemical Society of Japan, March 16-19, 2017, Keio University, Kanagawa,
Japan Nanami Mizukoshi, 〇Shunsuke Mizutani, Isao Mizota and Makoto Shimizu

137) (2PB-019) "Umpolung Reaction Followed by Intramolecular Amidation of N-Mono-substituted
α-Hydrazonoester"
The 97th Annual Meeting of The Chemical Society of Japan, March 16-19, 2017, Keio University, Kanagawa,
Japan Isao Mizota 〇Mizuho Iwami and Makoto Shimizu

136) (2PB-018) "Stereoselective Claisen Rearrangement and Their Application of α-Imino Allyl Esters Utilizing
N-Alkylation Reaction"
The 97th Annual Meeting of The Chemical Society of Japan, March 16-19, 2017, Keio University, Kanagawa,
Japan Isao Mizota 〇Tomoki Ejimai and Makoto Shimizu

135) (2PB-006) "Synthesis of Oxindoles Using Umpolung Reaction of 1H-Indazole-3-carboxylates"
The 97th Annual Meeting of The Chemical Society of Japan, March 16-19, 2017, Keio University, Kanagawa,
Japan Takanori Tanaka, 〇Mayuko Mori, Isao Mizota and Makoto Shimizu

134) (2E6-19) "Umpolung Reaction of the α-Imino Thioester Having a Cyclopropyl Group Followed by Tandem
Ring-Opening Reaction"
The 97th Annual Meeting of The Chemical Society of Japan, March 16-19, 2017, Keio University, Kanagawa,
Japan 〇Yusuke Yanagi, Isao Mizota and Makoto Shimizu

133) (2E6-18) "Synthesis of Unsaturated Amino Lactones by Tandem N-Alkylation/vinylogous Aldol Reaction of
β,γ-Alkyenyl-α-iminoster"
The 97th Annual Meeting of The Chemical Society of Japan, March 16-19, 2017, Keio University, Kanagawa,
Japan 〇Kenta Nakahama, Isao Mizota and Makoto Shimizu

132) (2E6-11) "Tandem Addition Reaction of α-Imino Thioester Using Umpolung Reaction"
The 97th Annual Meeting of The Chemical Society of Japan, March 16-19, 2017, Keio University, Kanagawa,
Japan 〇Yusuke Tsujimoto, Isao Mizota and Makoto Shimizu

131) (2E6-09) "Highly Efficient Sequential N,N-C-Trialkylation of α-Acyloxyimino ester"
The 97th Annual Meeting of The Chemical Society of Japan, March 16-19, 2017, Keio University, Kanagawa,
Japan 〇Isao Mizota, Mami Kawanishi and Makoto Shimizu

130) (2E6-02) "Diastereoselective Synthesis of α-Aminoamide: N-Alkylation and Intramolecular Amidation of
α-Hydrazonoester"
The 97th Annual Meeting of The Chemical Society of Japan, March 16-19, 2017, Keio University, Kanagawa,
Japan 〇Nanami Mizukoshi, Isao Mizota and Makoto Shimizu

129) (2E6-01) "Umpolung Reaction of N-Silyl-α-Imino Ester"
The 97th Annual Meeting of The Chemical Society of Japan, March 16-19, 2017, Keio University, Kanagawa,
Japan 〇Yurie Tadano, Isao Mizota and Makoto Shimizu

128) (1E6-32) "Tandem N-Alkylation/coupling Reaction of α-Aldimino Esters"
The 97th Annual Meeting of The Chemical Society of Japan, March 16-19, 2017, Keio University, Kanagawa,
Japan 〇Asako Higashino, Isao Mizota and Makoto Shimizu

127) (1E6-31) "Umpolung Reaction of N-Phosphinoyl-α-imino Ester"
The 97th Annual Meeting of The Chemical Society of Japan, March 16-19, 2017, Keio University, Kanagawa,
Japan 〇Shota Uchimizu, Isao Mizota and Makoto Shimizu

126) (1E6-30) "Synthesis of Multi-substituted 1,4-Benzoxazine Using Umpolung Reaction with 2-Oxo-1,4-
benzoxazine-3-carboxylates"
The 97th Annual Meeting of The Chemical Society of Japan, March 16-19, 2017, Keio University, Kanagawa,
Japan 〇Takanori Tanaka, Isao Mizota and Makoto Shimizu

125) "Umplung Reaction of N-Phosphinoyl α-Imino Ester"
47th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 5-6, 2016,
Toyohashi University of Technology, Aichi, Japan 〇Shota Uchimizu, Isao Mizota and Makoto Shimizu

124) "Umpolung Reaction of N-Silyl-α-imino Ester"
47th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 5-6, 2016,
Toyohashi University of Technology, Aichi, Japan 〇Yurie Tadano, Isao Mizota and Makoto Shimizu

123) (2P31) "Disastereoselective Tandem N-Alylation/Michael Addition of α-Imino Thioester"
47th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 5-6, 2016,
Toyohashi University of Technology, Aichi, Japan 〇Yusuke Tsujimoto, Isao Mizota and Makoto Shimizu

122) (2P27) "Umpolung Reaction of β-Cyclopropyl-α-imino Thioesters Followiong by Ring-opening"
47th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 5-6, 2016,
Toyohashi University of Technology, Aichi, Japan 〇Yusuke Yanagi, Isao Mizota and Makoto Shimizu

121) (2P24) "Selective Tandem N-Alkylatioon/Homo- and Cross-coupling Reaction of α-Aldimino Thioesters"
47th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 5-6, 2016,
Toyohashi University of Technology, Aichi, Japan 〇Asako Higashino, Isao Mizota and Makoto Shimizu

120) (2P18) "Tandem Additon Reaction Using Umpolung Reaction with 2-Oxo-1,4-benzoxazine-3-carboxylate
Derivatives"
47th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 5-6, 2016,
Toyohashi University of Technology, Aichi, Japan 〇Takanori Tanaka, Isao Mizota and Makoto Shimizu

119) (2P16) "Diastereoselective Synthesis of α-Aminoamide: N-Alkylation and Intramolecular Amidation of
α-Hydrazonoester"
47th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 5-6, 2016,
Toyohashi University of Technology, Aichi, Japan 〇Nanami Mizukoshi, Isao Mizota and Makoto Shimizu

118) (P-28) "Structural Effects of the Oxazaborolidine Derived from L-Threonine in the Reduction of
(Trifluoroacetyl)biphenyl Derivatives and meso-1,4-dioxane Derivatives"
The 9th Fluorous Science Symposium at Nagoya, October 7th, 2016, Nagoya University, Aichi, Japan
Isao Mizota Yoshio Onogawa, Hiroaki Shindo, Kenta Yamamoto, Iwao Hachiya and Makoto Shimizu

117) (FP-12) "Umpolung reaction of β-cyclopropyl-α-imino thioesters following by ring-opening"
The 6th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2016), September 27-28,
2016, Mie University, Mie 〇Yusuke Yanagi, Isao Mizota and Makoto Shimizu

116) (FP-11) "Diastereoselective synthesis of α-aminoamide: N-alkylation and intramolecular amidation of
α-hydrazonoester"
The 6th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2016), September 27-28,
2016, Mie University, Mie 〇Nanami Mizukoshi, Isao Mizota and Makoto Shimizu

115) (FP-10) "Selective tandem N-alkylation/homo- and cross-coupling reaction of α-aldimino thioester"
The 6th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2016), September 27-28,
2016, Mie University, Mie 〇Asako Higashino, Isao Mizota and Makoto Shimizu

114) (FP-9) "Diastereoselective tandem N-alkylation/Michael addition of α-imino thioester with Grignard
reagents"
The 6th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2016), September 27-28,
2016, Mie University, Mie 〇Yusuke Tsujimoto, Isao Mizota and Makoto Shimizu

113) (FP-8) "Umpolung reaction of N-phosphinoyl-α-imino ester"
The 6th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2016), September 27-28,
2016, Mie University, Mie 〇Shota Uchimizu, Isao Mizota and Makoto Shimizu

112) (FO-3) "Synthesis of multi-substituted 1,4-benzoxazine using umpolung reaction with 2-oxo-1,4-benzoxazine-
3-carboxylates"
The 6th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2016), September 27-28,
2016, Mie University, Mie 〇Takanori Tanaka, Isao Mizota and Makoto Shimizu

111) (FO-2) "Umpolung reaction of N-silyl-α-imino ester"
The 6th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2016), September 27-28,
2016, Mie University, Mie 〇Yurie Tadano, Isao Mizota and Makoto Shimizu

110) (3PC-044) "Tandem Umpolung Reaction of N-Trialkylsilyl α-Imino Ester"
The 96th Annual Meeting of The Chemical Society of Japan, March 24-27, 2016, Nihon University, Kyoto, Japan
Isao Mizota, 〇Yusuke Nakamura, and Makoto Shimizu

109) (3PC-037) "N-Alkylation of β,γ-Alkenyl α-Iminoester and Subsequent Lactonization"
The 96th Annual Meeting of The Chemical Society of Japan, March 24-27, 2016, Nihon University, Kyoto, Japan
Kana Aratake, 〇Kenta Nakahama, Isao Mizota and Makoto Shimizu

108) (3PC-034) "Development of Novel Synthesis of Dicarboxylic Acids Utilizing Selective Ring-opening
Reaction of α-Lactone"
The 96th Annual Meeting of The Chemical Society of Japan, March 24-27, 2016, Nihon University, Kyoto, Japan
Yoshinari Kobayashi, 〇Satoshi Umeshima, Isao Mizota and Makoto Shimizu

107) (3H1-32) "Umpolung Reacton of the α-Imino Thioester Having Cyclopropyl Group Followed by Tandem
Reaction and Its Application"
The 96th Annual Meeting of The Chemical Society of Japan, March 24-27, 2016, Nihon University, Kyoto, Japan
〇Yusuke Yanagi, Isao Mizota and Makoto Shimizu

106) (1H1-38) "Formal Total Synthesis of Artocarpin"
The 96th Annual Meeting of The Chemical Society of Japan, March 24-27, 2016, Nihon University, Kyoto, Japan
Isao Mizota and Makoto Shimizu

105) (1H1-34) "Selective Tandem N-Alkylation/Homo- and Cross-Coupling Reaction of α-Aldimino Thioesters"
The 96th Annual Meeting of The Chemical Society of Japan, March 24-27, 2016, Nihon University, Kyoto, Japan
〇Asako Higashino, Isao Mizota and Makoto Shimizu

104) (1H1-29) "Diastereoselective Tandem N-Alkylation/Michael Addition of α-Imino Thioester with Grignard
Reagents"
The 96th Annual Meeting of The Chemical Society of Japan, March 24-27, 2016, Nihon University, Kyoto, Japan
〇Yusuke Tsujimoto, Isao Mizota and Makoto Shimizu

103) (1H1-28) "The Synthesis of α-Quaternary Unsaturated Amino Esters Utilizing the Tandem N-Alkylation/
Claisen Rearrangement of α-Imino Allyl Ester"
The 96th Annual Meeting of The Chemical Society of Japan, March 24-27, 2016, Nihon University, Kyoto, Japan
〇Yoshinari Kobayashi, Isao Mizota and Makoto Shimizu

102) (1H1-07) "Umpolung Reaction of α-Hydrazonoester : Novel Synthesis of α-Aminoamide"
The 96th Annual Meeting of The Chemical Society of Japan, March 24-27, 2016, Nihon University, Kyoto, Japan
〇Nanami Mizukoshi, Isao Mizota and Makoto Shimizu

101) (1H1-06) "N-Alkylation of β,γ-Alkenyl α-Iminoester and Subsequent Regioselective Nucleophilic Addition
to Conjugated Iminium Salt"
The 96th Annual Meeting of The Chemical Society of Japan, March 24-27, 2016, Nihon University, Kyoto, Japan
〇Kana Aratake, Isao Mizota and Makoto Shimizu

100) (2P24) "Tandem Umpolung Reaction of α-Imino Allyl Esters Followed by Claisen Rearrangement and a
Mechanistic Study"
46th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 7-8, 2015, Mie
University, Mie, Japan 〇Yoshinari Kobayashi, Isao Mizota and Makoto Shimizu

99) (FP-10) "SYNTHETIC STUDY OF MATEMONE CONTAINING AN OXINDOLE USING 1,2-AZA-
BROOK REARRANGEMENT AS A KEY REACTION "
The 5th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2015), September 29-30,
2015, Mie University, Mie 〇Hayao Imazato, Isao Mizota and Makoto Shimizu

98) (FO-8) "TANDEM UMPOLUNG REACTION/CLAISEN REARRANGEMENT OF α-IMINO ALLYL
ESTER AND A MECHANISTIC STUDY"
The 5th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2015), September 29-30,
2015, Mie University, Mie 〇Yoshinari Kobayashi, Isao Mizota and Makoto Shimizu

97) (3 PC-016) "Tandem N-Alkylation/Michael Addition with Various Organometallic Reagents to α-Imino
Thioester" The 95th Annual Meeting of The Chemical Society of Japan, March 26-29, 2015, Nihon University,
Chiba, Japan, Yun Tesong, 〇Yusuke Tsujimoto, Isao Mizota and Makoto Shimizu

96) (3 PC-015) "Umpolung Reaction of α-Imino Amides with Various Nucleophiles"
The 95th Annual Meeting of The Chemical Society of Japan, March 26-29, 2015, Nihon University, Chiba, Japan
Toshikazu Fukaya, 〇Nanami Mizukoshi, Isao Mizota and Makoto Shimizu

95) (3 PC-014) "Diastereoselective Tandem N-Alkylation/Nucleophilic Addition Reaction of α-Aldimino
Thioesters" The 95th Annual Meeting of The Chemical Society of Japan, March 26-29, 2015, Nihon University,
Chiba, Japan, Yuji Nakajima, 〇Asako Higashino, Isao Mizota and Makoto Shimizu

94) (3 PC-013) "Umpolung Reaction of N-Silyl α-Imino Ester"
The 95th Annual Meeting of The Chemical Society of Japan, March 26-29, 2015, Nihon University, Chiba, Japan
Isao Mizota, 〇Yurie Tadano and Makoto Shimizu

93) (3 PC-012) "Umpolung Reaction of α-Imino Thioester Having a Cyclopropyl Group with Grignard Reagents"
The 95th Annual Meeting of The Chemical Society of Japan, March 26-29, 2015, Nihon University, Chiba, Japan
Takayoshi Morimoto, 〇Yusuke Yanagi, Isao Mizota and Makoto Shimizu

92) (3 E3-28) "Sequential N-Alkylation/Vinylogous Aldol Reaction of β,γ-Alkenyl-α-iminoester"
The 95th Annual Meeting of The Chemical Society of Japan, March 26-29, 2015, Nihon University, Chiba, Japan
Isao Mizota and Makoto Shimizu

91) (2 E1-18) "Tandem N-Alkylation/Selective Cross Coupling Reaction α-Aldimino Thioesters with
α-Aldimino Ester"
The 95th Annual Meeting of The Chemical Society of Japan, March 26-29, 2015, Nihon University, Chiba, Japan
〇Yuji Nakajima, Isao Mizota and Makoto Shimizu

90) (1 E2-52) "Tandem N-Alkylation/Stereoselective Claisen Rearrangement of α-Imino Allyl Esters Utilizing
Umpolung Reaction"
The 95th Annual Meeting of The Chemical Society of Japan, March 26-29, 2015, Nihon University, Chiba, Japan
〇Toshikazu Fukaya, Isao Mizota and Makoto Shimizu

89) (1 E2-51) "Tandem Umpolung Reaction of α-Imino Allyl Esters Followed by Claisen Rearrangement and
a Mechanistic Study"
The 95th Annual Meeting of The Chemical Society of Japan, March 26-29, 2015, Nihon University, Chiba, Japan
〇Yoshinari Kobayashi, Isao Mizota and Makoto Shimizu

88) (1 E3-31) "Tandem Ring Opening Reaction Using Umpolung Reaction of α-Imino Thioester Having a
Cyclopropyl Group"
The 95th Annual Meeting of The Chemical Society of Japan, March 26-29, 2015, Nihon University, Chiba, Japan
〇Takayosi Morimoto, Isao Mizota and Makoto Shimizu

87) (1 E3-06) "Tandem N-Alkylation/Michael Addition of α-Imino Thioester"
The 95th Annual Meeting of The Chemical Society of Japan, March 26-29, 2015, Nihon University, Chiba,
Japan 〇Yun Tesong, Isao Mizota and Makoto Shimizu

86) (2P69) "Tandem N-Alkylation / Nucleophilic Addition Reaction of α-Aldimino Thioesters"
45th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 29-30, 2014,
Chubu University, Aichi, Japan 〇Yuji Nakajima, Isao Mizota and Makoto Shimizu

85) (2P27) "Tandem Reaction Using Umpolung Reaction of α-Imino Thioester Having a Cyclopropyl Group"
45th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 29-30, 2014,
Chubu University, Aichi, Japan ○Takayoshi Morimoto, Isao Mizota and Makoto Shimizu

84) (2P21) "Tandem N-Alkylation / Michael Addition of α-Imino Thioester with Several Electrophiles"
45th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 29-30, 2014,
Chubu University, Aichi, Japan 〇Yun, Isao Mizota and Makoto Shimizu

83) (2P20) "Stereoselective Claisen Rearrangement of α-Imino Allyl Esters Utilizing N-Alkylation Reaction"
45th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 29-30, 2014,
Chubu University, Aichi, Japan 〇Toshikazu Fukaya, Isao Mizota and Makoto Shimizu

82) "Exploration into a new dicarboxylic acid possessing a carbocyclic structure forthe aluminum electrolytic
capacitors of high performance"
New Technology presentation Meetings!, November 27, 2014, Tokyo, Japan ○Isao Mizotaand Makoto Shimizu

81) (SO2, P38) "Tandem N-Alkylation / Nucleophilic Addition Reaction of α-Aldimino Esters Utilizing a New
Flow System"
The Ninth International Symposium on Integrated Synthesis (ISIS-9), November 14-15, 2014, Awaji, Japan Yuji
Nakajima, Takanori Sano, ○Isao Mizota, and Makoto Shimizu

80) (FP-8) "Stereoselective Claisen Rearrangement of α-Imino Allyl Esters Utilizing N-Alkylation Reaction"
The 4th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2014), September 17-18,
2014, Mie University, Mie○Toshikazu Fukaya, Isao Mizota and Makoto Shimizu

79) (FP-7) "Tandem N-Alkylation / Nucleophilic Addition Reaction of α-Aldimino Thioesters"
The 4th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2014), September 17-18,
2014, Mie University, Mie○Yuji Nakajima, Isao Mizota and Makoto Shimizu

78) (FO-2) "Tandem N-Alkylation / Michael Addition of α-Imino Thioester with Several Electrophiles"
The 4th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2014), September 17-18,
2014, Mie University, Mie○Tesong Yun, Isao Mizota and Makoto Shimizu

77) (FO-1) "Tandem Reaction Using Umpolung Reaction of α-Imino Thioester Having a Cyclopropyl Group"
The 4th International Synmposium for Sustainability by Engineering at MIU (IS2EMU 2014), September 17-18,
2014, Mie University, Mie○Takayoshi Morimoto, Isao Mizota and Makoto Shimizu

76) (2P004) "Claisen Rearrangement of Aluminum Enolate Derived from α-Imino Allyl Ester via an Umpolung
Reacton"
The XXVI International Conference on Organometallic Chemistry, July 13-18, 2014, Sapporo, Japan 〇Isao
Mizota
and Makoto Shimizu

75) (3 B6-55) "Stereoselective Claisen Rearrangement of α-Imino Allyl Esters Utilizing N-Alkylation Reaction"
The 94th Annual Meeting of The Chemical Society of Japan, March 27-30, 2014, Nagoya University, Aichi,
Japan 〇Toshikazu Fukaya, Isao Mizota and Makoto Shimizu

74) (3 PC-055) "Intermolecular Nucleophilic Addition Reaction of α-Imino Ester Using C-Silylation Followed by
Aza-Brook Rearrangement"
The 94th Annual Meeting of The Chemical Society of Japan, March 27-30, 2014, Nagoya University, Aichi,
Japan Takafumi Katano, 〇Hikaru Wakatsuki, Isao Mizota and Makoto Shimizu

73) (3 PC-029) "Synthetic Study of Biologically Active Cudraflavone B "
The 94th Annual Meeting of The Chemical Society of Japan, March 27-30, 2014, Nagoya University, Aichi,
Japan Kana Taniguchi, 〇Akihiro Obara, Isao Mizota and Makoto Shimizu

72) (3 PC-024) "Desymmetrization of Heterocyclic Compounds Formed by Cycloaddition Reactions of the Diene
Derived from 2,3-Dimethoxy-2,3-dimethyl-1,4-dioxane"
The 94th Annual Meeting of The Chemical Society of Japan, March 27-30, 2014, Nagoya University, Aichi,
Japan Toshihiro Yamamoto, 〇Hiroaki Shindo, Isao Mizota, Iwao Hachiya and Makoto Shimizu

71) (3 B7-16) "Tandem N-Alkylation / Michael Addition to α-Imino Thioester"
The 94th Annual Meeting of The Chemical Society of Japan, March 27-30, 2014, Nagoya University, Aichi,
Japan 〇Yun Tesong, Isao Mizota and Makoto Shimizu

70) (3 B8-12) "Syntheses of Quaternary Amino Acid Derivatives Utilizing an N-Alkylation Reaction to
β,γ-Alkynyl α-Imino Ester"
The 94th Annual Meeting of The Chemical Society of Japan, March 27-30, 2014, Nagoya University, Aichi,
Japan 〇Isao Mizota and Makoto Shimizu

69) (3 B8-01) "Tandem N-Alkylation / Nucleophilic Addition Reaction of α-Aldimino Thioesters " The 94th
Annual Meeting of The Chemical Society of Japan, March 27-30, 2014, Nagoya University, Aichi, Japan 〇Yuji
Nakajima, Isao Mizota and Makoto Shimizu

68) (2 B8-30) "Synthetic Study of Biologically Active Artocarpin in Short Steps via a Coupling Reaction"
The 94th Annual Meeting of The Chemical Society of Japan, March 27-30, 2014, Nagoya University, Aichi,
Japan 〇Kana Taniguchi, Isao Mizota and Makoto Shimizu

67) (2 B8-16) "Tandem Reaction Using Umpolung Reaction of α-Imino Thioester Having a Cyclopropyl Group"
The 94th Annual Meeting of The Chemical Society of Japan, March 27-30, 2014, Nagoya University, Aichi,
Japan 〇Takayoshi Morimoto, Isao Mizota and Makoto Shimizu

66) (1 B8-57) "Synthetic Study of Heterocyclic Compounds Using Cycloaddition Reaction of the Dienes Derived
from 2,3-Dimethoxy-2,3-dimethyl-1,4-dioxane Derivatives"
The 94th Annual Meeting of The Chemical Society of Japan, March 27-30, 2014, Nagoya University, Aichi,
Japan 〇Toshihiro Yamamoto, Isao Mizota, Iwao Hachiya and Makoto Shimizu

65) "Umpolung Reaction of α-Imino Ester and Application to Flow Synthesis"
Grant-in-Aid for Scientific Research on Innovative Areas, Ministry of Education, Culture, Sports, Science, and
Technology, Japan, The third training camp for young people, December 21-22, 2013, Tottori, Japan 〇Isao Mizota

64) (P8) "Tandem N-Alkylation-Addition Reaction of α-Aldimino Ester and Application to a New Flow System"
The Eighth International Symposium on Integrated Synthesis (ISIS-8), November 29 - December 1, 2013, Nara,
Japan Takanori Sano, 〇Isao Mizota and Makoto Shimizu

63) (2P23) "Nucleophilic Addition Reaction of α-Imino Esters Using C-Silylation Followed by Aza-Brook
Rerrangement"
44th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 2-3,
2013, Shizuoka University, Shizuoka, Japan 〇Takafumi Katano, Isao Mizota and Makoto Shimizu

62) (2P09) "Synthetic Study of Biologically Active Artocarpin by Coupling Reaction."
44th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 2-3, 2013,
Shizuoka University, Shizuoka, Japan 〇Kana Taniguchi, Isao Mizota and Makoto Shimizu

61) (2P07) "Synthetic Study of Heterocyclic Compounds Using 3-Dimethylene-1,4-dioxane Derived from
2,3-Dimethoxy-2,3-dimetyl-1,4-dioxane."
44th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 2-3, 2013,
Shizuoka University, Shizuoka, Japan 〇Toshihiro Yamamoto, Isao Mizota, Iwao Hachiya and Makoto Shimizu

60) “Reductive Ring Opening Reactions of Azetidine-3-ones and O-Alkyl Oximes Promoted by Titanium Tetraiodide "
The 16th the Society of Iodine Science (SIS) Symposium, September 18, 2013, Chiba, Japan 〇Iwao Hachiya,
Shingo Hata, Daisuke Fukuda, Shizuka Ariga, Takafumi Nishi, Isao Mizota and Makoto Shimizu

59) “Synthetic Study of Biologically Active Artocarpin by Coupling Reaction"
The 3rd International Symposium for Sustainability by Engineering at MIU, September 17, 2013, Mie, Japan
〇Kana Taniguchi, Isao Mizota, Iwao Hachiya and Makoto Shimizu

58) “Nucleophilic Addition Reaction of α-Imino Esters Using C-Silylation Followed by Aza-Brook
Rearrangement"
The 3rd International Symposium for Sustainability by Engineering at MIU, September 17, 2013, Mie, Japan
〇Takafumi Katano, Isao Mizota, Iwao Hachiya and Makoto Shimizu

57) “Synthesis of Tetrahydro-4-quinolones by Cyclization of α-Imino Esters via Aza-Brook Rearrangement and
Application to (+)-Duocarmycin A"
The 3rd International Symposium for Sustainability by Engineering at MIU, September 17, 2013, Mie, Japan
〇Haruna Katsurayama, Isao Mizota and Makoto Shimizu

56) “Synthetic Study of Heterocyclic Compounds Using Cycloaddition Reaction of the Diene Derived from
2,3-Dimethoxy-2,3-dimethyl-1,4-dioxane"
The 3rd International Symposium for Sustainability by Engineering at MIU, September 17, 2013, Mie, Japan
〇Toshihiro Yamamoto, Isao Mizota, Iwao Hachiya and Makoto Shimizu

55) (P1B-07) "Iodo Aldol Reaction of γ-Alkoxy-α,β-alkynyl Ketone Derivatives Promoted by Titanium Tetraiodide."
60th Symposium on Organometallic Chemistry, Japan, September 12-14, 2013, Gakusyuin University, Tokyo, Japan
Iwao Hachiya, Shingo Ito, Shota Kayaki,〇Isao Mizota, and Makoto Shimizu

54) "Integrated Synthesis of Nitrogen-Containing Compounds Using Characteristic Features of Imines." Seminor for
the young researcher, July 12, 2013, Mie University, Mie, Japan 〇Isao Mizota

53) (3 PB-018) “Diastereoselective Mannich Reaction Using Umpolung Reaction and Oxidation of α-Imino Esters.”
The 93rd Annual Meeting of The Chemical Society of Japan, March 22-25, 2013, Ritsumeikan University, Shiga,
Japan Isao Mizota, 〇Yuji Nakajima and Makoto Shimizu

52) (3 PB-017) “Tandem Reaction Using Umpolung Reaction of α-Imino Ester Having a Cyclopropyl Group”
The 93rd Annual Meeting of The Chemical Society of Japan, March 22-25, 2013, Ritsumeikan University, Shiga,
Japan Takanori Sano, 〇Takayoshi Morimoto, Isao Mizota and Makoto Shimizu

51) (3 PB-016) “Umpolung Reaction of α-Iminothioester with Various Nucleophiles”
The 93rd Annual Meeting of The Chemical Society of Japan, March 22-25, 2013, Ritsumeikan University, Shiga,
Japan Chihiro Ueda, 〇Tesong Yun, Isao Mizota and Makoto Shimizu

50) (3 PB-015) “Syntheses of γ,δ-Unsaturated Amino Esters Utilizing an Umpolung Reaction to α-Imino Allyl
Esters Followed by Claisen Rearrangement”
The 93rd Annual Meeting of The Chemical Society of Japan, March 22-25, 2013, Ritsumeikan University, Shiga,
Japan Isao Mizota, 〇Yumi Miwa and Makoto Shimizu

49) (3 E6-16) “Successive Carbon-Carbon Bond Formation Reaction Using Umpolung Reaction to α-Imino
Thioester”
The 93rd Annual Meeting of The Chemical Society of Japan, March 22-25, 2013, Ritsumeikan University, Shiga,
Japan 〇Chihiro Ueda, Isao Mizota and Makoto Shimizu

48) (3 E6-12) “N-Alkylation of α-Imino Ester Followed by Nucleophilic Addition Reaction and Application to
a New Flow System.”
The 93rd Annual Meeting of The Chemical Society of Japan, March 22-25, 2013, Ritsumeikan University, Shiga,
Japan 〇Takanori Sano, Isao Mizota and Makoto Shimizu

47) (3 E6-11) “Nucleophilic Addition Reaction of α-Imino Esters Using C-Silylation Followed by Aza-Brook
Rerrangement”
The 93rd Annual Meeting of The Chemical Society of Japan, March 22-25, 2013, Ritsumeikan University, Shiga,
Japan 〇Takafumi Katano, Isao Mizota and Makoto Shimizu

46) (3 E6-06) “Stereoselective Claisen Rearrangement of α-Imino Allyl Esters Using an Umpolung Reaction”
The 93rd Annual Meeting of The Chemical Society of Japan, March 22-25, 2013, Ritsumeikan University, Shiga,
Japan Isao Mizota, 〇Toshikazu Fukaya, and Makoto Shimizu

45) (3 E6-04) “Claisen Rearrangement of α-Imino Allyl Ester Utilizing N-Alkylation”
The 93rd Annual Meeting of The Chemical Society of Japan, March 22-25, 2013, Ritsumeikan University, Shiga,
Japan 〇Isao Mizota and Makoto Shimizu

44) (2 E6-28) “Synthetic Study of Biologically Active Artocarpin by Coupling Reaction” The 93rd Annual Meeting
of The Chemical Society of Japan, March 22-25, 2013, Ritsumeikan University, Shiga, Japan 〇Kana Taniguchi,
Isao Mizota
and Makoto Shimizu

43) (1 E6-07) “Synthetic Study of Heterocyclic Compounds Using Cycloaddition Reaction of the Diene Derived
from 2,3-Dimethoxy-2,3-dimetyl-1,4-dioxane.”
The 93rd Annual Meeting of The Chemical Society of Japan, March 22-25, 2013, Ritsumeikan University, Shiga,
Japan 〇Toshihiro Yamamoto, Isao Mizota, Iwao Hachiya and Makoto Shimizu

42) (2P11) “N-Alkylation of α-Imino Ester Followed by Electrophlic Addition Reaction and Application to a New
Flow System.”
43rd Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 10-11, 2012,
Nagoya Institute of Technology, Aichi, Japan 〇Takanori Sano, Isao Mizota and Makoto Shimizu

41) (1P13) “Synthetic Study of Biologically Active Artocarpin”
43rd Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 10-11, 2012,
Nagoya Institute of Technology, Aichi, Japan 〇Kana Taniguchi, Isao Mizota and Makoto Shimizu

40) (1D06) “Umpolung Reaction to α-Imino Thioester Followed by Successive Carbon-Carbon Bond Formation Reaction”
43rd Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 10-11, 2012,
Nagoya Institute of Technology, Aichi, Japan 〇Chihiro Ueda, Isao Mizota and Makoto Shimizu

39) (Poster11) “Claisen Rarrangement of α-Imino Allyl Ester Using An Umpolung Reaction”
IUPAC 8th International Conference on Novel Materials and Synthesis (NMS-VIII) 22nd International
Symposium on Fine Chemistry and Functional Polymers (FCFP-XXII), October 14-19, 2012, Xi’An, China
Isao Mizota and Makoto Shimizu

38) (21) “Halo Aldol Reactions of γ-Alkoxy-α,β-alkynyl Ketone Derivatives Promoted by Titanium Tetraiodide"
The 15th the Society of Iodine Science (SIS) Symposium, September 11, 2012, Chiba, Japan 〇Iwao Hachiya,
Shingo Ito, Syota Kayaki, Isao Mizota and Makoto Shimizu

37) (P-52) “Synthetic Study of Biologically Active Artocarpin” The 29th Seminar on Synthetic Organic Chemistry
The 70th Anniversary symposium on Organic Synthesis, September 5-7, 2012, Shizuoka, Japan 〇Kana Taniguchi,
Isao Mizota and Makoto Shimizu

36) (P-47) “Claisen Rearrangement of α-Imino Allyl Ester Using Umpolung Reaction” The 29th Seminar on Synthetic
Organic Chemistry The 70th Anniversary symposium on Organic Synthesis, September 5-7, 2012, Shizuoka, Japan
Isao Mizota and Makoto Shimizu

35) (P-46) “N-Alkylation of α-Imino Ester Followed by Electrophlic Addition Reaction and Its Flow Synthesis.”
The 29th Seminar on Synthetic Organic Chemistry The 70th Anniversary symposium on Organic Synthesis,
September 5-7, 2012, Shizuoka, Japan 〇Takanori Sano, Isao Mizota and Makoto Shimizu

34) (3 K6-40) “Synthetic Study of Biologically Active Artocarpin”
The 92nd Annual Meeting of The Chemical Society of Japan, March 25-28, 2012, Keio University, Kanagawa,
Japan Isao Mizota, 〇Kana Taniguchi and Makoto Shimizu

33) (3 PA-027) “Development of New Synthetic Routes of 3,4-Ethylenedioxythiophene(EDOT) and Its Analogues”
The 92nd Annual Meeting of The Chemical Society of Japan, March 25-28, 2012, Keio University, Kanagawa,
Japan Isao Mizota, 〇Toshihiro Yamamoto, Iwao Hachiya and Makoto Shimizu

32) (1 K6-43) “Carbon-Carbon Bond Formation Reaction Using Umpolung Reaction to .alpha.-Imino Thioester”
The 92nd Annual Meeting of The Chemical Society of Japan, March 25-28, 2012, Keio University, Kanagawa, Japan
〇Chihiro Ueda, Isao Mizota and Makoto Shimizu

31) (1 K6-35) “N-Alkylation of α-Imino Ester Followed by Electrophilic Addition Reaction and Its Flow Synthesis”
The 92nd Annual Meeting of The Chemical Society of Japan, March 25-28, 2012, Keio University, Kanagawa, Japan
〇Takanori Sano, Isao Mizota and Makoto Shimizu

30) “Halo-aldol Reaction of γ-Alkoxy-α,β-alkynylketone Derivatives Promoted by Titanium iodide”
14th the Society of Iodine Science symposium, September 11, 2011, Chiba University, Chiba, Japan Iwao
Hachiya, Shingo Itoh, Syouta Kayaki, Isao Mizota and Makoto Shimizu

29) “Tandem N-Alkylation to α-Imino Ester, Followed by Electrophilic Addition Reaction using microreactor”
Grant-in-Aid for Scientific Research on Innovative Areas, The Ministry of Education, Culture, Sports, Science,
and Technology, Japan, The fourth young person symposium, June 11, 2011, Mie University, Mie, Japan 〇Isao
Mizota
and Makoto Shimizu

28) (3 C2-01) “Study of N-Allylideneamine Synthesis and 1,4- and 1,2- Double Nucleophilic Addition”
The 91th Annual Meeting of The Chemical Society of Japan, March 26-29, 2011, Kanagawa University,
Kanagawa, Japan 〇Shun Agatani, Isao Mizota, Iwao Hachiya and Makoto Shimizu

27) (4 C1-10) “Umpolung N-Alkylation of α-Imino Ester Followed by Intermolecular Nucleophilic Addition Reaction”
The 91th Annual Meeting of The Chemical Society of Japan, March 26-29, 2011, Kanagawa University,
Kanagawa, Japan Isao Mizota, ○Takanori Sano and Makoto Shimizu

26) (4 C1-11) “Umpolung Reaction of α-Imino Thioester”
The 91th Annual Meeting of The Chemical Society of Japan, March 26-29, 2011, Kanagawa University,
Kanagawa, Japan Isao Mizota, 〇Chihiro Ueda and Makoto Shimizu

25) (4 C1-12) “Claisen Rearrangement of α-Imino Allyl Esters Using Umpolung Reaction”
The 91th Annual Meeting of The Chemical Society of Japan, March 26-29, 2011, Kanagawa University,
Kanagawa, Japan 〇Isao Mizota and Makoto Shimizu

24) (2E08) “Synthesis of quaternary amino esters using umpolung reaction and Claisen rearrangement of α-imino ester”
41th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 6-7, 2010, Toyohashi
University of Technology, Aichi, Japan ○Isao Mizota and Makoto Shimizu

23) (P-16) “Claisen Rearrangement of α-Imino Allyl Ester Using Umpolung Reaction”
The 27th Seminar on Synthetic Organic Chemistry, September 2-4, 2010, Kobe, Japan Isao Mizota and
Makoto Shimizu

22) (P-31) “Synthesis of 2,2-Disubstituted Indolin-3-ones by Intramolecular Cyclization of α-Imino Esters via
Aza-Brook Rearrangement”
The 27th Seminar on Synthetic Organic Chemistry, September 2-4, 2010, Kobe, Japan 〇Yuki Takao, Isao
Mizota
and Makoto Shimizu

21) (3 F5-50) “Claisen Rearrangement of α-Imino Allyl Esters via Umpolung Reaction”
The 90th Annual Meeting of The Chemical Society of Japan, March 26-29, 2010, Kinki University, Osaka,
Japan ○Isao Mizota and Makoto Shimizu

20) (3 F5-51) “Synthesis of 2,2-Disubstituted Indoline-3-one via N-Alkylation to α-Imino Esters,
Followed by Intramolecular Cyclization”
The 90th Annual Meeting of The Chemical Society of Japan, March 26-29, 2010, Kinki
University, Osaka, Japan Isao Mizota, ○Yuki Takao and Makoto Shimizu

19) (3 F7-51) “Reductive Self-coupling Reaction of Imines and Aldehydes Induced by Strontium Metal”
The 90th Annual Meeting of The Chemical Society of Japan, March 26-29, 2010, Kinki University, Osaka, Japan
Norikazu Miyoshi, Tadashi Kouno, Makoto Wada, ○Sei Matsunaga, Isao Mizota and Makoto Shimizu

18) (2 PB-036) “N-Alkylation to α-Imino Ester, Followed by Electrophilic Addition Reaction”
The 90th Annual Meeting of The Chemical Society of Japan, March 26-29, 2010, Kinki
University, Osaka, Japan Isao Mizota, ○Yuki Matsuda and Makoto Shimizu

17) (2 PB-041) “Study of N-Allylideneamine Synthesis and a 1,4- and 1,2- Double Nucleophilic Addition to
N
-Allylideneamine Derived from Acrolein”
The 90th Annual Meeting of The Chemical Society of Japan, March 26-29, 2010, Kinki University, Osaka, Japan
Isao Mizota, ○Shun Agatani, Iwao Hachiya and Makoto Shimizu

16) (2I05) “Claisen Rearrangement of .α-Imino Esters via Umpolung Reaction”
40th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 7-8, 2009, Gifu
University, Gifu, Japan ○Isao Mizota and Makoto Shimizu

15) (A32) “Amino Acid and Valerolactam Syntheses Using Double Nucleophilic Addition Reaction To
N-Allylideneamines”
IUPAC 5th International Symposium on Novel Materials and Synthesis (NMS-V) 19th International Symposium
on Fine Chemistry and Functional Polymers (FCFP-XIX) 3rd Symposium on Power Sources for Energy Storage
and their Key Materials (PS-III), October 18-22, 2009, Shanghai, China ○Isao Mizota, Iwao Hachiya and
Makoto Shimizu

14) (P-51) “1.4- and 1,2-Double Nucleophilic Addition Reaction to N-Allylideneamines”
The 26th Seminar on Synthetic Organic Chemistry, September 16-18, 2009, Maebashi, Japan ○Isao Mizota,
Yuri Matsuda, Iwao Hachiya
and Makoto Shimizu

13) (4 G3-15) “N-Alkylation of α-Imino Esters Followed by Nucleophilic Addition to Various Electrophiles”
The 89th Annual Meeting of The Chemical Society of Japan, March 27-30, 2009, Nihon University, Chiba, Japan
Isao Mizota and Makoto Shimizu

12) (4 G3-29) “Study of a 1,4- and 1,2- Double Nucleophilic Addition Reaction Using N-Allylideneamines as
a Latent Acrolein” The 89th Annual Meeting of The Chemical Society of Japan, March 27-30, 2009, Nihon
University, Chiba, Japan Isao Mizota, ○Mami Kawanishi, Iwao Hachiya and Makoto Shimizu.

11) (43) “The Synthesis of N-Allylideneamime and Their Use for the Double Nucleophilic Addition of Ketene
Silyl (Thio)Acetals and Trimethylsilyl Cyanide”
Asian Collaborative Forum for Women Researchers in Science and Technology Encourage and Empower the
Next Generation, December 20, 2008, Mie University, Mie, Japan ○Isao Mizota, Iwao Hachiya and Makoto Shimizu

10) (1O10) “1,4- and 1,2-Double Nucleophilic Addition Reaction to N-Allylideneamines”
39th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 8-9, 2008,
Nagoya University, Aichi, Japan ○Isao Mizota, Iwao Hachiya and Makoto Shimizu

9) (PS-10) “The Synthesis of N-Allylideneamime and Their Use for the Double Nucleophilic Addition of Ketene
Silyl (Thio)Acetals and Trimethylsilyl Cyanide”
Third International Conference on Advanced Organic Synthesis Directed toward the Ultimate Efficiency and
Practicability, May 26-27, 2008, Otsu Prince Hotel, Shiga, Japan ○Isao Mizota, Iwao Hachiya and Makoto
Shimizu

8) (3 J3-51) “Study of a 1,4- and 1,2- Double Nucleophilic Addition to N-Allylideneamine Derived from Acrolein”
The 88th Annual Meeting of The Chemical Society of Japan, March 26-30, 2008, Rikkyo University, Tokyo,
Japan ○Isao Mizota, Iwao Hachiya and Makoto Shimizu

7) (3 J3-52) “Synthetic Study of δ-Lactam Using a 1,4- and 1,2- Double Nucleophilic Addition to N-Allylideneamine
Derived from Acrolein”
The 88th Annual Meeting of The Chemical Society of Japan, March 26-30, 2008, Rikkyo University, Tokyo,
Japan Isao Mizota, ○Yuri Matsuda, Iwao Hachiya and Makoto Shimizu

6) (2I15) “Study of a 1,4- and 1,2- Double Nucleophilic Addition to N-Allylideneamine Derived from Acrolein”
38th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November 10-11, 2007,
Mie University, Mie, Japan ○Isao Mizota, Iwao Hachiya and Makoto Shimizu

5) (IL 65) “Double nucleophilic addition of ketene silyl (thio)acetals and trimethylsilyl cyanide to
N-allylideneamine”
IUPAC 3rd International Symposium on Novel Materials and Synthesis (NMS-III) & 17th International
Symposium on Fine Chemistry and Functional Polymers (FCFP-XVIII), October 17-21, 2007, Shanghai, China
Isao Mizota, Iwao Hachiya and Makoto Shimizu

4) (2 C8-49) “Study of a 1,4- and 1,2- Double Nucleophilic Addition to N-Allylideneamine
Derived from Acrolein”
The 87th Annual Meeting of The Chemical Society of Japan, March 25-28, 2007, Kansai
University, Osaka, Japan Isao Mizota, Iwao Hachiya and Makoto Shimizu

3) (2J12) “Synthesis of N-Allylideneamines and Their Use for the Double Nucleophilic Addition
of Ketene Silyl Acetals and Trimethylsilyl Cyanide”
37th Annual Meeting of Union of Chemistry-Related Societies in Chubu Area, Japan, November
12-13, 2006, Aichi Institute of Technology, Aichi, Japan Isao Mizota, Iwao Hachiya and Makoto Shimizu

2) (O-8) “Synthesis of N-Allylideneamines and Their Use for the Double Nucleophilic
Addition of Ketene Silyl Acetals and Trimethylsilyl Cyanide”
90th Symposium on Organic Synthesis, Japan, November 9-10, 2006, Waseda University, Tokyo,
JapanIsao Mizota, Iwao Hachiya and Makoto Shimizu

1) (1 J1-47)“First Synthesis of N-Allylideneamine Derived from Acrolein and Study of a Double Nucleophilic
Addition”
The 86th Annual Meeting of The Chemical Society of Japan, March 27-30, 2006, Nihon University, Chiba, Japan
Shiho Kawai, Isao Mizota and Makoto Shimizu

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