発表論文 (After 2010)NEWS&FAQ
Umpolung Reaction of α-Tosyloximino Ester Using a Flow System, Kazuki Ota,
Shinya Fukumoto, Taiki Iwase, Isao Mizota, Makoto Shimizu, Iwao Hachiya,
Synlett 2020, 31, 1930-1936.
Industry-academia Collaboration Aiming to Develop the Aluminum Electrolytic Capacitors of High Performance, Isao Mizota, Iwao Hachiya, Keisuke Kato, Naoya Torikai, Yorozu Yokomori, Bulltein of the Tokai Chemical Industry Society 2020, 280, 10-14.
Domino 1,4- and 1,6-Addition Reactions of Ketene Silyl Acetals to Dialkynyl Imines Promoted by Aluminum Chloride: Synthesis of Multifunctionalized β‑Lactams, I. Hachiya, Kenta Nakamura, Masaya Hara, Koki Sato, Makoto Shimizu, J. Org. Chem. 2019, 84, 14770-14794.
Titanium Tetraiodide/Trimethylsilyl Iodide Synergistically Induced Cyclization of N‑(2-Cyanophenyl)benzamides into 2‑Aryl-4-iodoquinazolines,. I. Hachiya, S. Nagoshi, Makoto Shimizu, ACS Omega 2019, 4, 10463-10473.
Development of Novel Reaction Utilizing Iodination Ability of TiI4, Iwao Hachiya, Isao Mizota, Makoto Shimizu, J. Synth. Org. Chem. Jpn. 2017, 75, 1226-1237.
Titanium tetraiodide-mediated diastereoselective iodo-aldol and Mannich reactions of γ-alkoxy-α,β-alkynyl ketone derivatives, Kai Yashiro, Shingo Ito, Shota Kayaki, Keito Sakata, Isao Mizota, Iwao Hachiya, Makoto Shimizu, Tetrahedron 2016, 72, 6875-6885.
Synthesis of (±)-muscopyridine analogue using ring-expansion reaction of cyclic β-keto ester via conjugate addition to alkynyl imine, Iwao Hachiya, Naoki Kugisaki, Ryosuke Agata, Hisae Matsumoto, Yoshiyasu Yamada, Makoto Shimizu, Tetrahedron, 2015, 71, 5824-5829.
2-Aryl-4-quinolone Synthesis Using the Thermal Rearrangement of Iminocyclobutenones，Iwao Hachiya, Keiichi Yokoyama, Akinori Ito, and Makoto Shimizu，Heterocycles, 2015, 90, (1), 97-103.
N-Alkylation of α-Iminophosphonates and application to Horner-Wadsworth-Emmons Reaction, Makoto Shimizu, Masasato Tateishi, and Isao Mizota, Chem. Lett., 2014, 43, (11), 1752-1754.
Chiral β-Lactam Synthesis through the Enantioselective Reduction of Iminocyclobutenones and Thermal Rearrangement of Aminocyclobutenones, Iwao Hachiya, Akinori Ito, and Makoto Shimizu, Asian J. Org. Chem., 2014, 3, (5), 614-618.
Titanium Tetraiodide-Mediated Organic Reactions, Tsuyoshi Haneishi, Iwao Hachiya, and Makoto Shimizu, Arabian J. Sci. Eng., 2014, 39,(9), 6599-6616.
Chemoselective reductions and iodinations using titanium tetraiodide, Iwao Hachiya and Makoto Shimizu，Tetrahedron Lett., 2014, 55, (17), 2781-2788.
Diastereoselective Iodo Aldol Reaction of g-Alkoxy a,b-Alkynyl Ketone Derivatives Promoted by Titnium Tetraiodide，Iwao Hachiya, Shingo Ito, Shota Kayaki, and Makoto Shimizu, Asian J. Org. Chem., 2013, 2, (11), 931-934.
Synthesis of a-Amino Ketones and O-Alkyloximes by Titanium Tetrahalide Promoted Ring-opening Reaction of 2-Mono-substitued Azetidine-3-ones and Their O-Alkyloximes, S. Ariga, S. Hata, D. Fukuda, T. Nishi, I. Hachiya, and M. Shimizu, Heterocycles, 2012, 86, (2), 1187-1210.
Synthesis of Nitrogen-containing Heterocycles Using Conjugate Addition Reactions of Nucleophiles to a,b-Unsaturated Imines, Iwao Hachiya, Isao Mizota, and Makoto Shimizu, Heterocycles, 2012, 85, (5), 993-1016.
Regioselctive Ring-opening Reaction of 2-Mono-substituted Azetidin-3-ones Promoted by the Combines Use of Titanium Tetraiodide and Its Chloro or Bromo Counterpart, Shingo Hata, Daisuke Fukuda, Iwao Hachiya, and Makoto Shimizu, Heterocycles, 2012, 84, (1), 301-307.
Reductive Aminopropylation of Ketene Silyl (Thio)acetals Leading to the Synthesis of δ-Amino Esters, Isao Mizota, Shun Agatani, Iwao Hachiya, Makoto Shimizu, Tetrahedron Lett., 2011, 52, (41) 5388-5391.
Double Nucleophilic Addition Reaction to Acrolein with Ketene Silyl Acetals and Allylborolanes Catalyzed by Proline, Makoto Shimizu, Mami Kawanishi, Akinori Itoh, Isao Mizota, and Iwao Hachiya, Chem. Lett., 2011, 40, (8) 862-863.
Titanium Tetraiodide Promoted Reductive Enolate Formation of a- Tosyloxy Ketone Derivatives and Aldol Reaction with Aldehydes, Iwao Hachiya, Takao Inagaki, Yasuhisa Ishihara, and Makoto Shimizu, Bull. Chem. Soc. Jpn., 2011, 84, (4) 419-421.
Titanium Tetraiodide Promoted Tandem Prins Reaction of Alkynes with Acetals: Synthesis of (Z,Z)-1,5-Diiodo-1,3,5-triarylpenta-1,4-dienes, Makoto Shimizu, Kanako Okura, Takuya Arai, and Iwao Hachiya, Chem. Lett., 2010, 39, (10) 1052-1054.
Use of N-Allylidene-1,1-diphenylethanamine as a Latent Acrolein Synthon in the Double Nucleophilic Addition Reaction of Ketene Silyl (Thio)acetals and Allylborolanes Makoto Shimizu, Mami Kawanishi, Isao Mizota, and Iwao Hachiya, Org. Lett., 2010, 12, (16), 3571-3573.
Synthesis of 3,4-Ethylenedioxythiophene (EDOT) from (Z)-But-2-ene-1,4-diol or But-2-yne-1,4-diol, Iwao Hachiya, Tomohiro Matsumoto, Tatsuhiko Inagaki, Atsushi Takahashi, and Makoto Shimizu, Heterocycles, 2010, 82, (1), 449-460.
A New Method for the Synthesis of Multi-substituted Pyrroles of Biological Interest by Double Nucleophilic Addition to a,b-Unsaturated Imines, Atsushi Takahashi, Shiho Kawai, Iwao Hachiya, and Makoto Shimizu, Eur. J. Org. Chem., 2010, (1) 191-200.
Reductive Aldol and Mannich-Type Reactions of Azetidin-3-ones Promoted by Titanium Tetraiodide, Shingo Hata, Daisuke Fukuda, Iwao Hachiya, and Makoto Shimizu, Chem. Asian J., 2010, 5, (1), 473-477.
Facile Synthesis and Ring-Opening of 4-(Tributylstannyl)pyrrolidine-2-carboxylates, Makoto Shimizu, Hiromi Ando, Hitoshi Shibuya, and Iwao Hachiya, Heterocycles, 2010, 80, (2), 773-778.
Industry-academia Collaboration Aiming to Develop the Aluminum Electrolytic Capacitors of High Performance, Isao Mizota, Iwao Hachiya, Keisuke Kato, Naoya Torikai, Yorozu Yokomori, Bulltein of the Tokai Chemical Industry Society 2020, 280, 10-14.
Domino 1,4- and 1,6-Addition Reactions of Ketene Silyl Acetals to Dialkynyl Imines Promoted by Aluminum Chloride: Synthesis of Multifunctionalized β‑Lactams, I. Hachiya, Kenta Nakamura, Masaya Hara, Koki Sato, Makoto Shimizu, J. Org. Chem. 2019, 84, 14770-14794.
Titanium Tetraiodide/Trimethylsilyl Iodide Synergistically Induced Cyclization of N‑(2-Cyanophenyl)benzamides into 2‑Aryl-4-iodoquinazolines,. I. Hachiya, S. Nagoshi, Makoto Shimizu, ACS Omega 2019, 4, 10463-10473.
Development of Novel Reaction Utilizing Iodination Ability of TiI4, Iwao Hachiya, Isao Mizota, Makoto Shimizu, J. Synth. Org. Chem. Jpn. 2017, 75, 1226-1237.
Titanium tetraiodide-mediated diastereoselective iodo-aldol and Mannich reactions of γ-alkoxy-α,β-alkynyl ketone derivatives, Kai Yashiro, Shingo Ito, Shota Kayaki, Keito Sakata, Isao Mizota, Iwao Hachiya, Makoto Shimizu, Tetrahedron 2016, 72, 6875-6885.
Synthesis of (±)-muscopyridine analogue using ring-expansion reaction of cyclic β-keto ester via conjugate addition to alkynyl imine, Iwao Hachiya, Naoki Kugisaki, Ryosuke Agata, Hisae Matsumoto, Yoshiyasu Yamada, Makoto Shimizu, Tetrahedron, 2015, 71, 5824-5829.
2-Aryl-4-quinolone Synthesis Using the Thermal Rearrangement of Iminocyclobutenones，Iwao Hachiya, Keiichi Yokoyama, Akinori Ito, and Makoto Shimizu，Heterocycles, 2015, 90, (1), 97-103.
N-Alkylation of α-Iminophosphonates and application to Horner-Wadsworth-Emmons Reaction, Makoto Shimizu, Masasato Tateishi, and Isao Mizota, Chem. Lett., 2014, 43, (11), 1752-1754.
Chiral β-Lactam Synthesis through the Enantioselective Reduction of Iminocyclobutenones and Thermal Rearrangement of Aminocyclobutenones, Iwao Hachiya, Akinori Ito, and Makoto Shimizu, Asian J. Org. Chem., 2014, 3, (5), 614-618.
Titanium Tetraiodide-Mediated Organic Reactions, Tsuyoshi Haneishi, Iwao Hachiya, and Makoto Shimizu, Arabian J. Sci. Eng., 2014, 39,(9), 6599-6616.
Chemoselective reductions and iodinations using titanium tetraiodide, Iwao Hachiya and Makoto Shimizu，Tetrahedron Lett., 2014, 55, (17), 2781-2788.
Diastereoselective Iodo Aldol Reaction of g-Alkoxy a,b-Alkynyl Ketone Derivatives Promoted by Titnium Tetraiodide，Iwao Hachiya, Shingo Ito, Shota Kayaki, and Makoto Shimizu, Asian J. Org. Chem., 2013, 2, (11), 931-934.
Synthesis of a-Amino Ketones and O-Alkyloximes by Titanium Tetrahalide Promoted Ring-opening Reaction of 2-Mono-substitued Azetidine-3-ones and Their O-Alkyloximes, S. Ariga, S. Hata, D. Fukuda, T. Nishi, I. Hachiya, and M. Shimizu, Heterocycles, 2012, 86, (2), 1187-1210.
Synthesis of Nitrogen-containing Heterocycles Using Conjugate Addition Reactions of Nucleophiles to a,b-Unsaturated Imines, Iwao Hachiya, Isao Mizota, and Makoto Shimizu, Heterocycles, 2012, 85, (5), 993-1016.
Regioselctive Ring-opening Reaction of 2-Mono-substituted Azetidin-3-ones Promoted by the Combines Use of Titanium Tetraiodide and Its Chloro or Bromo Counterpart, Shingo Hata, Daisuke Fukuda, Iwao Hachiya, and Makoto Shimizu, Heterocycles, 2012, 84, (1), 301-307.
Reductive Aminopropylation of Ketene Silyl (Thio)acetals Leading to the Synthesis of δ-Amino Esters, Isao Mizota, Shun Agatani, Iwao Hachiya, Makoto Shimizu, Tetrahedron Lett., 2011, 52, (41) 5388-5391.
Double Nucleophilic Addition Reaction to Acrolein with Ketene Silyl Acetals and Allylborolanes Catalyzed by Proline, Makoto Shimizu, Mami Kawanishi, Akinori Itoh, Isao Mizota, and Iwao Hachiya, Chem. Lett., 2011, 40, (8) 862-863.
Titanium Tetraiodide Promoted Reductive Enolate Formation of a- Tosyloxy Ketone Derivatives and Aldol Reaction with Aldehydes, Iwao Hachiya, Takao Inagaki, Yasuhisa Ishihara, and Makoto Shimizu, Bull. Chem. Soc. Jpn., 2011, 84, (4) 419-421.
Titanium Tetraiodide Promoted Tandem Prins Reaction of Alkynes with Acetals: Synthesis of (Z,Z)-1,5-Diiodo-1,3,5-triarylpenta-1,4-dienes, Makoto Shimizu, Kanako Okura, Takuya Arai, and Iwao Hachiya, Chem. Lett., 2010, 39, (10) 1052-1054.
Use of N-Allylidene-1,1-diphenylethanamine as a Latent Acrolein Synthon in the Double Nucleophilic Addition Reaction of Ketene Silyl (Thio)acetals and Allylborolanes Makoto Shimizu, Mami Kawanishi, Isao Mizota, and Iwao Hachiya, Org. Lett., 2010, 12, (16), 3571-3573.
Synthesis of 3,4-Ethylenedioxythiophene (EDOT) from (Z)-But-2-ene-1,4-diol or But-2-yne-1,4-diol, Iwao Hachiya, Tomohiro Matsumoto, Tatsuhiko Inagaki, Atsushi Takahashi, and Makoto Shimizu, Heterocycles, 2010, 82, (1), 449-460.
A New Method for the Synthesis of Multi-substituted Pyrroles of Biological Interest by Double Nucleophilic Addition to a,b-Unsaturated Imines, Atsushi Takahashi, Shiho Kawai, Iwao Hachiya, and Makoto Shimizu, Eur. J. Org. Chem., 2010, (1) 191-200.
Reductive Aldol and Mannich-Type Reactions of Azetidin-3-ones Promoted by Titanium Tetraiodide, Shingo Hata, Daisuke Fukuda, Iwao Hachiya, and Makoto Shimizu, Chem. Asian J., 2010, 5, (1), 473-477.
Facile Synthesis and Ring-Opening of 4-(Tributylstannyl)pyrrolidine-2-carboxylates, Makoto Shimizu, Hiromi Ando, Hitoshi Shibuya, and Iwao Hachiya, Heterocycles, 2010, 80, (2), 773-778.